Pregnant women who have a BMI>30 or report snoring are at higher risk for developing obstructive sleep apnea in pregnancy (about a 1 in 5 chance). Sleep apnea is a sleep disorder that affects the quality of your sleep and your daytime functioning. Normally during sleep, air moves through the throat and in and out of the lungs at a regular rhythm. In a person with sleep apnea, air movement is periodically diminished or stopped, and breathing is abnormal because of narrowing or closure of the throat. Sleep apnea in pregnancy has been associated with the development of gestational hypertension, preeclampsia, eclampsia, and preterm delivery.
The standard treatment for obstructive sleep apnea in the general population is a Continuous Positive Airway Pressure (CPAP) machine. The goal of this two-part study is to a) identify pregnant women with sleep apnea between 16 and 22 weeks of gestation, and b) determine the effectiveness of CPAP as a therapy for sleep apnea in pregnancy. This study is a multicenter randomized controlled trial that aims to identify 3000 pregnant women with obstructive sleep apnea.
Principal Investigator: Dr. Harish Sehdev