The Penn PCOS Center is conducting a clinical trial to compare the effects of medications on metabolic risk factors such as weight, blood pressure, glucose, and cholesterol levels in overweight/obese women with Polycystic Ovary Syndrome (PCOS) over a six-month period. Study participants will be randomized to one of three groups: 1) Birth Control Pills (to improve male hormone levels), 2) Metformin (to improve insulin levels) or 3) both Birth Control Pills and Metformin.
Your participation in this study will consist of a screening visit, followed by 5 study visits. During this time, you will receive physical exams, laboratory assessments, ultrasound, bone density scans, lifestyle and nutritional advice, medications, and compensation.
Women with a diagnosis of PCOS, between the ages of 18 to 40 years, who are overweight or obese, and not seeking pregnancy, may be eligible to participate.
If you are interested in seeing if you qualify for this study, click here or call 215.662.7727
Anuja Dokras, MD, PhD