Penn Medicine BioBank – PCOS
Cardiovascular Disease Biomarkers and Metabolic Phenotypes in Polycystic Ovary Syndrome
The purpose of this study is to determine whether novel biomarkers related to cardiovascular disease are elevated in women with PCOS. In this pilot study, we will use previously collected blood samples to compare levels of these new biomarkers in adult women with PCOS and healthy controls. PCOS subjects and controls are recruited through women’s health clinics within the University of Pennsylvania Health System. We will look at clinical symptoms and hormone levels in the PCOS subjects, as well as traditional cardiovascular risk measures when analyzing these biomarkers. The relationship between these biomarker levels, cardiovascular risk measures, and characteristics of PCOS will clarify the cardiovascular risk in this population and potentially identify new therapeutic targets.
Dr. Anuja Dokras-Jagasia, MD, PhD