Emergency Contraception Study

This study is being conducted at the University of Pennsylvania to test the effectiveness of three different hormonal emergency contraception pills available for women who weigh 80 kg (176 pounds) or more and who have had unprotected intercourse within the last 3 days. The emergency contraception being tested is all commercially available and would be provided to qualified participants free of charge. The emergency contraception qualified study participants may receive is Plan B One Step® (1.5 mg levonorgestrel), two doses of Plan B One Step®, or Ella® (30 mg ulipristal acetate 30 mg).

This study will investigate the safety and effectiveness of the three emergency contraception methods as compared to each other, to determine if there is a method that works best for women who are overweight and obese. This one-month study will also be looking at any health changes or side effects that may occur during the study period. Study participation involves about four phone calls and up to two in-person visits. Participants will be compensated for their time and travel for completing the visits.

Qualified participants:

  • Healthy women ages 18-40,

  • Weight at least (176 pounds),

  • Have had unprotected sex in the last 72 hours (3 days),

  • Have regular menstrual periods, 

  • In need of emergency contraception, and

  • Willing to avoid use of any hormonal or intrauterine contraception until the end of the study

Participants who qualify will receive:

  • Compensation for travel

  • Medical exams

  • Emergency Contraception and Condoms

Click here to complete the study pre-screener.

Study Coordinator: Sandra Loza-Avalos 215-615-0381

© 2017 by Penn Medicine Women's Health Clinical Research Center

University of Pennsylvania, Philadelphia PA

(215) 662-7727