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Annovera Tampon Study


The Women's Health Clinical Research Center at University of Pennsylvania is currently recruiting healthy women who have regular periods for a research study. The purpose of the study is to find out if Annovera, a contraceptive vaginal ring that releases hormones into your body to prevent pregnancy, and tampons used at the same time affects the amount of hormones released into your blood.


If you qualify for the study, you will be asked to use the Annovera contraceptive vaginal system (ring) for two 21-day cycles, one cycle with tampon use and one cycle without tampon use. A new Annovera vaginal system will be provided for each cycle and tampons will be used during 3 days of one of the Annovera cycles.


If you choose to participate, you will be asked to come to the study clinic for about 23 visits over 4 ½ months. During these visits you will have blood taken and at some visits you will have your blood pressure measured and will take a urine pregnancy test.


Participation in this study involves:

  • 23 visits to the study site

  • physical and pelvic exams

  • blood and urine sampling

  • completion of a brief daily diary

  • brief use of a contraceptive ring and oral contraceptive pills


Participants who qualify will receive:

  • Compensation for time and travel

  • Medical exams


If you are interested in participating in this study, complete the online pre-screener here or contact 215.662.7727 for more information

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