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A research study on the effects of lifestyle modification in overweight women with unexplained fertility.


Qualified participants are:

  •  overweight women (BMI ≥ 30)

  •  18-40 years old

  •  regular menstrual periods

  •  at least 1 year of infertility

  •  seeking pregnancy

Participants will:


  • have regular visits to 3701 Market Street

  • wear a Fitbit (activity tracking watch)

  • take study medications

  • keep a diary

  • use Nutrisystem meals

  • undergo physical exams, blood work, clinical imaging to determine if fallopian tubes are open, and semen analysis (male partner)

  • undergo ovarian stimulation with intrauterine insemination

Principal Investigator:
Christos Coutifaris, MD, PhD

FOR MORE INFORMATION contact the research coordinator at 215-615-3664 or email, and reference the FIT-PLESE study. 

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